| Description | This product is a recombinant Human antibody provided by CreativeBiolabs. The antibody is specific for ATP binding cassette subfamily B member 11. It can be used for ATP binding cassette subfamily B member 11 detection in Western Blot, Flow Cytometry and Immunofluorescence. It was expressed in mammalian cells (293F or CHO) with antibody encoding genes and purified by affinity chromatography. Each lot of this antibody is quality control tested by SDS-PAGE and SEC-HPLC analysis. For highly sensitive assays, we recommend the ultrapurified form of the product, which has a lower endotoxin limit than standard antibody, less than 1 EU/mg or even 0.1 EU/mg. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human, Rat |
| Epitope | The epitope is in the C-terminal half of BSEP. |
| Isotype | IgG1 |
| Expression Species | HEK293F or CHO Cell line |
| Conjugation | Unconjugated, also available for Biotin, HRP, FITC and PE-labeled form. |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg, determined by LAL method |
| Purification | Purified with Protein A or G affinity chromatography |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | WB; FC; IF |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | ABCB11 |
| Alternative Name | ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11; Progressive Familial Intrahepatic Cholestasis 2; ATP-Binding Cassette Sub-Family B Member 11; BSEP; ABC Member 16, MDR/TAP Subfamily; Bile Salt Export Pump; Sister P-Glycoprotein; MDR/TAP Subfamily; ABC Member 16; EC 3.6.3.44; EC 3.6.3; PFIC-2; ABC16; BRIC2; PFIC2; PGY4; SPGP |
| Gene ID | 8647 |
| UniProt | O95342 |
| Research Area | Signal Pathway |
| Related Disease | Cancer such as hepatocellular carcinoma and hepatoblastoma |
