| Sub Cat | Target Species | Isotype | Application | Affinity | |
|---|---|---|---|---|---|
| V3S-1124-YC632 | Human | IgG2 kappa | Block; FuncS | 0.057 nM | |
| V3S-0622-YC11 | Human | IgG2 kappa | Block; FuncS | 0.024 nM |
| Description | The anti-ADCYAP1R1 antibody was generated by immunizing with the ADCYAP1R1 (also known as PAC1) extracellular domain protein. The antibody binds to human and cynomolgus PAC1 and can inhibit binding of PAC1 to PACAP. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human |
| Epitope | The epitope is located in the extracellular domain. |
| Affinity | KD = 0.057 nM |
| Isotype | IgG2 kappa |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | Block; FuncS |
| Application Notes | The antibody is recommended for detection of ADCYAP1R1 by Block, FuncS assays. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | ADCYAP1R1 |
| Alternative Name | PAC1; PAC1R; PACAPR; PACAPRI; pituitary adenylate cyclase-activating polypeptide type I receptor; PACAP receptor 1; PACAP type I receptor; PACAP-R1; adenylate cyclase; activating polypeptide 1 (pituitary) receptor type I; pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop; pituitary adenylate cyclase-activating; polypeptide type 1 receptor |
| Gene ID | 117 |
| UniProt | P41586 |
| Research Area | Neuroscience; Signal Pathway |
