ANGPT1 / ANGPT2 Specific Neutra™ Antibody (V3S-0324-FY4), Human IgG (CAT#: V3S-0324-FY4)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target

Summary

Description This product is a human antibody that binds angiopoietin-1 and angiopoietin-2. It inhibits neovascularization in a mouse model of OIR and can also be used in PK profiling studies in cynomolgus monkeys.
Clonality Monoclonal
Host Species Human
Target Species Human, Cynomolgus
Isotype Human IgG

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and SEC-HPLC
Endotoxin <1 EU/mg
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within a week. For longer storage, aliquot and store at -20°C.

Applications

Application Inhib; FuncS

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target ANGPT1 / ANGPT2
Alternative Name Angiopoietin 1; ANG-1; Angiopoietin-1; KIAA0003; AGP1; AGPT; ANG1
Gene ID 284
UniProt Q15389
Related pathway MIF Mediated Glucocorticoid Regulation and TGF-Beta Pathway
Research Area Cancer Research
Related Disease Cancer; ocular neovascular
For research use only, not directly for clinical use.
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