Anti-APP (aa 1-42) Neutralizing Antibody (V3S-0622-YC883) (CAT#: V3S-0622-YC883)

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Datasheet

MSDS

COA

Sub Cat Immunogen Epitope Isotype  
V3S-1124-YC790 Amylospheroid 42 IgG2b kappa Inquiry
V3S-0622-YC894 Synthetic Aβ1-40 IgG1 Inquiry
V3S-0622-YC905 C-terminus peptide of amyloid β (1-40) Aβ1-40 IgG Inquiry
V3S-0622-YC911 Aβ1-40 oligomer Aβ1-40 IgG Inquiry
V3S-0622-YC906 C-terminus peptide of amyloid β (1-42) Aβ1-42 IgG Inquiry
V3S-0622-YC916 WtAβ 1-42 protofibril Aβ1-42 IgG Inquiry
V3S-0622-YC918 E22P-Aβ9-35 peptide Aβ9-35 IgG Inquiry
V3S-0622-YC907 N-terminus peptide of amyloid β N-terminus IgG Inquiry
V3S-0622-YC861 Amyloid β peptides IgG Inquiry
V3S-0622-YC863 Human amyloid-beta peptide IgG Inquiry
V3S-0622-YC867 Aβ42-CC Oligomers IgG3 Inquiry
V3S-0622-YC909 Human amyloid precursor proteinsignal peptide IgG2a Inquiry
V3S-0622-YC917 Aβ42arc in protofibril conformation IgG Inquiry
V3S-0622-YC925 Ka (spanning the β-secretase cleavage site in human APP) IgG1 Inquiry
V3S-0622-YC926 Ka (spanning the β-secretase cleavage site in human APP) IgG2b Inquiry
V3S-0622-YC928 Fibrilliar Aβ protein IgG3 Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description This product is a monoclonal antibody derived from mouse, which can specifically recognize APP. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation.
Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free.
Clonality Monoclonal
Host Species Mouse
Target Species Human
Immunogen Amylospheroid 42
Isotype IgG2b kappa

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.

Applications

Application FuncS
Application Notes The antibody is recommended for detection of APP by FuncS assay.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target APP
Alternative Name APP; Amyloid Beta; amyloid beta (A4) precursor protein
Gene ID 351
UniProt P05067
Research Area Neuroscience
For research use only, not directly for clinical use.
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