| Description | BET v1 (aa 1-74) Antibody (V3S-0324-FY21) is a human IgG4 antibody. It has been observed to augment the binding of IgE to Bet v 1, thereby qualifying as an 'enhancing antibody'. BET v1 (aa 75-160) Antibody (V3S-0324-FY22) is a human IgG1 monoclonal antibody. It can special recognized the epitope of AA 75-160 for Bet v 1. Antibody (V3S-0324-FY22) blocked IgE anti-Bet v 1 reactivity. Conversely, BET v1 (aa 75-160) antibody (V3S-0324-FY22) impedes the binding of IgE from atopic patients to Bet v 1, while antibody (V3S-0324-FY21) promotes it. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human |
| Epitope | Amino acids 1-74 |
| Isotype | Human IgG4 |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | WB; ELISA; Block |
| Application Notes | ELISA: 0.2 µg/mL |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | BET v1 |
| Alternative Name | Bet v I allergen; the major birch pollen allergen; Betula pendula allergen 1 |
| Research Area | Immunology |
