Anti-C3 Neutralizing Antibody (V3S-0522-YC3019) (CAT#: V3S-0522-YC3019)

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Datasheet

MSDS

COA

Sub Cat Host Species Immunogen Isotype Application  
V3S-1124-YC136 Human IgG Neut Inquiry
V3S-0522-YC3021 Human IgG ELISA; Neut Inquiry
V3S-0522-YC8054 Human Human complement component 3 IgG ELISA; Neut Inquiry
V3S-0622-YC1148 Human IgG FuncS Inquiry
V3S-0822-YC443 Mouse Human C3a IgG1 kappa ELISA; IP; Neut; WB Inquiry
V3S-0822-YC444 Mouse Purified native human C3b protein IgG1 kappa ELISA; FC; Block; IF; RIA Inquiry
V3S-0324-FY77 Mouse IgG1 Inhib; ELISA; WB Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description This product is a monoclonal antibody derived from Human (Homo sapiens), which can specifically recognize Complement component 3. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation.
Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free.
Clonality Monoclonal
Host Species Human
Target Species Human
Isotype IgG

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.

Applications

Application Neut
Application Notes The antibody is recommended for detection of C3 by Neut assay.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target C3
Alternative Name Complement Component 3; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 1; Complement Component C3a; Complement Component C3b; C3a Anaphylatoxin; Prepro-C3; CPAMD1; Epididymis Secretory Sperm Binding Protein Li 62p; Acylation-Stimulating Protein Cleavage Product; Complement Component C3; HEL-S-62p; AHUS5; ARMD9; ASP; C3a; C3b
Gene ID 718
UniProt P01024
Research Area Immunology; Neuroscience
Related Disease Multiple acute and chronic disease
For research use only, not directly for clinical use.
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