| Sub Cat | Host Species | Epitope | Isotype | Application | |
|---|---|---|---|---|---|
| V3S-1124-YC84 | Mouse | In the Nt and ECL2 domain. | IgG1 | ELISA; FC; RET | |
| V3S-0522-YC3078 | Human | In the Nt and ECL2 domain. | IgG | Block |
| Description | This product is a monoclonal antibody derived from Mouse (Mus musculus), which can specifically recognize Chemokine (C-C motif) receptor 5. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation. Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free. |
| Clonality | Monoclonal |
| Host Species | Mouse |
| Target Species | Human |
| Immunogen | L1.2-CCR5+ cells |
| Epitope | Located in the Nt and ECL2 domain. |
| Isotype | IgG1 |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and/or SEC-HPLC |
| Endotoxin | <1 EU/mg, determined by LAL method |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C. |
| Application | ELISA; FC; RET |
| Application Notes | The antibody is recommended for detection of CCR5 by ELISA, FC, RET assays. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | CCR5 |
| Alternative Name | Chemokine (C-C Motif) Receptor 5 (Gene/Pseudogene); HIV-1 Fusion Coreceptor; CC-CKR-5; ChemR13; CMKBR5; CCR-5; C-C Motif Chemokine Receptor 5 A159A; Chemokine (C-C Motif) Receptor 5; Chemokine Receptor CCR5; CD195 Antigen; C-C CKR-5; CCCKR5; IDDM22; CD195; CKR-5; CKR5 |
| Gene ID | 1234 |
| UniProt | P51681 |
| Research Area | Neuroscience; Immunology |
