| Description | This product is a humanized monoclonal antibody that reacts with CD63. The antibody is able to mediate ADCC by recruiting effector cell activity. It is shown that the mAb induces a specific and dose-dependent MDA-MB-231 target cell lysis, both with adherent and non-adherent effector cells. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human |
| Affinity | 50 nM |
| Isotype | IgG kappa |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | FC; ELISA; IHC |
| Application Notes | The antibody is recommended for detection of CD63 by FC, ELISA, IHC (1/20-1/200) assays. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | CD63 |
| Alternative Name | CD63 Molecule; Lysosomal-Associated Membrane Protein 3; Ocular Melanoma-Associated Antigen; CD63 Antigen (Melanoma 1 Antigen); Melanoma-Associated Antigen ME491; Tetraspanin-30; Granulophysin; CD63 Antigen; Tspan-30; AR7BD-33-11A |
| Gene ID | 967 |
| UniProt | P08962 |
| Related pathway | Response to elevated platelet cytosolic Ca2+; Innate Immune System |
| Research Area | Cardiovascular; Immunology |
