Anti-CSF1R Neutralizing Antibody (V3S-0522-YC6361) (CAT#: V3S-0522-YC6361)

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Datasheet

MSDS

COA

Sub Cat Immunogen Isotype Application Affinity  
V3S-1124-YC364 CSF1R IgG ELISA; Inhib 0.36 nM Inquiry
V3S-0522-YC6364 CSF1R IgG ELISA; Inhib 2.5 nM Inquiry
V3S-0522-YC6369 CSF1R IgG ELISA; Inhib 0.77 nM Inquiry
V3S-0522-YC6371 CSF1R IgG ELISA; Inhib 0.78 nM Inquiry
V3S-0822-YC874 Recombinant human M-CSF R/CD115 IgG1 Neut; WB Inquiry
V3S-0822-YC875 Recombinant human M-CSF R/CD115 IgG1 Neut; WB Inquiry
V3S-0522-YC5665 IgG2a kappa ELISA; FC; WB; Inhib Inquiry
V3S-0822-YC876 Recombinant human MCSF Receptor extracellular domain. IgG1 Neut; WB Inquiry
V3S-1022-YC3249 A human CSF1R extracellular domain Fc fusion, hCSF1R ECD.506-Fc IgG ELISA; Block Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description This product is a monoclonal antibody derived from Mouse (Mus musculus), which can specifically recognize Colony stimulating factor 1 receptor. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation.
Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free.
Clonality Monoclonal
Host Species Mouse
Target Species Human
Immunogen CSF1R
Affinity KD = 0.36 nM, determined by surface plasmon resonance.
Isotype IgG

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.

Applications

Application ELISA; Inhib
Application Notes The antibody is recommended for detection of CSF1R by ELISA, Inhib assays.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target CSF1R
Alternative Name FMS; CSFR; FIM2; HDLS; C-FMS; CD115; CSF-1R; M-CSF-R
Gene ID 1436
UniProt P07333
Research Area Cardiovascular; Immunology
Related Disease Rheumatoid arthritis, Multiple sclerosis
For research use only, not directly for clinical use.
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