| Sub Cat | Isotype | Application | Affinity | |
|---|---|---|---|---|
| V3S-1124-YC480 | ELISA; Neut; Inhib | |||
| V3S-0622-YC167 | IgG1 kappa | Inhib; WB; IP | 13 nM | |
| V3S-0622-YC168 | IgG1 kappa | Inhib; WB; IP | 62 nM |
| Description | The humanized antibody h1F5 bind with high affinity to NiV F and HeV F glycoproteins. This antibody broadly inhibited and neutralized NiV-M, NiV-B and HeV. This product has been determined using Neutralization assay and Inhibition assay. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Nipah virus (NiV), Hendra virus (HeV) |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA; Neut; Inhib |
| Application Notes | The Inhibition assay showed that the Ab broadly inhibited NiV-M, NiV-B and HeV with IC50 ranging between 0.2 and 1.3 µg/mL. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | F glycoprotein |
| Alternative Name | Fusion glycoprotein |
| Research Area | Infectious Disease |
| Related Disease | Respiratory illness, severe encephalitis |