| Sub Cat | Affinity | |
|---|---|---|
| V3S-1124-YC1740 | 2.642 pM | |
| V3S-0522-YC7028 | 6.393 pM | |
| V3S-0522-YC7029 | 7.356 pM | |
| V3S-0522-YC7030 | 11.45 pM |
| Description | This product is a monoclonal antibody derived from Human (Homo sapiens), which can specifically recognize Growth Differentiation Factor 15. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation. Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human, Cynomolgus, Mouse, Rat |
| Epitope | Located in the knucke domain of human GDF15. |
| Affinity | KD = 2.642 pM, determined by surface plasmon resonance. |
| Isotype | IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and/or SEC-HPLC |
| Endotoxin | <1 EU/mg, determined by LAL method |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C. |
| Application | ELISA; Block |
| Application Notes | The antibody is recommended for detection of GDF15 by ELISA, Block assays. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | GDF15 |
| Alternative Name | Growth Differentiation Factor 15; Prostate Differentiation Factor; Non-Steroidal Anti-Inflammatory Drug-Activated Gene-1; Placental Bone Morphogenetic Protein; Macrophage Inhibitory Cytokine 1; NSAID-Activated Gene 1 Protein; NSAID-Regulated Gene 1 Protein; Placental TGF-Beta; GDF-15; MIC-1; NAG-1; |
| Gene ID | 9518 |
| UniProt | Q99988 |
| Research Area | Signal Pathway |
