Anti-GDF15 Neutralizing Antibody (V3S-0622-YC1658) (CAT#: V3S-0622-YC1658)

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  • fig1

Datasheet

MSDS

COA

Sub Cat Immunogen Isotype Application Affinity  
V3S-1022-YC3010 6×His tagged recombinant human GDF15 (His-rhGDF15) IgG1 kappa WB; ELISA 0.21 nM (mFc-rhGDF15) Inquiry
V3S-1022-YC3011 6×His tagged recombinant human GDF15 (His-rhGDF15) IgG1 kappa WB; ELISA 0.22 nM (mFc-rhGDF15) Inquiry
V3S-1022-YC3012 6×His tagged recombinant human GDF15 (His-rhGDF15) IgG1 kappa WB; ELISA 0.19 nM (mFc-rhGDF15) Inquiry
V3S-0622-YC188 Recombinant MIC-1 protein was converted to cDNA IgG ELISA; Inhib Inquiry
V3S-0622-YC189 Recombinant MIC-1 protein was converted to cDNA IgG ELISA; Inhib Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description These monoclonal antibodies bind human GDF15. Some of these clones can block angiogenic function of MIC-1. The antibodies can be used for research of GDF15-related diseases (e.g. Cachexia).
Clonality Monoclonal
Host Species Mouse
Target Species Human
Immunogen Recombinant GDF15 protein
Isotype Mouse IgG

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.

Applications

Application ELISA, Inhib, WB
Application Notes The antibodies are recommended for ELISA, Western blot or Inhibition assay.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target GDF15
Alternative Name GDF2; growth differentiation factor 2; BMP9; HHT5; BMP-9
Gene ID 2658
UniProt Q9UK05
Research Area Signal Pathway
For research use only, not directly for clinical use.
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