Anti-GDF15 Neutralizing Antibody (V3S-0622-YC1658) (CAT#: V3S-0622-YC1658)

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Datasheet

MSDS

COA

Sub Cat Immunogen Isotype Application Affinity  
V3S-1124-YC378 IgG FuncS Inquiry
V3S-0622-YC1659 IgG1 kappa FuncS Inquiry
V3S-0622-YC1650 PCan065 Construct IgG2b ELISA; FC Inquiry
V3S-1022-YC3010 6×His tagged recombinant human GDF15 (His-rhGDF15) IgG1 kappa WB; ELISA 0.21 nM (mFc-rhGDF15) Inquiry
V3S-1022-YC3011 6×His tagged recombinant human GDF15 (His-rhGDF15) IgG1 kappa WB; ELISA 0.22 nM (mFc-rhGDF15) Inquiry
V3S-1022-YC3012 6×His tagged recombinant human GDF15 (His-rhGDF15) IgG1 kappa WB; ELISA 0.19 nM (mFc-rhGDF15) Inquiry
V3S-0622-YC188 Recombinant MIC-1 protein was converted to cDNA IgG ELISA; Inhib Inquiry
V3S-0622-YC189 Recombinant MIC-1 protein was converted to cDNA IgG ELISA; Inhib Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description This product is a monoclonal antibody derived from mouse, which can specifically recognize GDF15. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation.
Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free.
Clonality Monoclonal
Host Species Mouse
Target Species Human
Immunogen Recombinant human BMP9 protein
Isotype IgG

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.

Applications

Application FuncS
Application Notes The antibody is recommended for detection of GDF15 by FuncS assay.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target GDF15
Alternative Name GDF2; growth differentiation factor 2; BMP9; HHT5; BMP-9
Gene ID 2658
UniProt Q9UK05
Research Area Signal Pathway
For research use only, not directly for clinical use.
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