| Description | This is a neutralizing antibody clone PC39-50I specific for HIV-1 Env protein, derived from human. This antibody is a broadly neutralizing antibody, which has high binding affinity with V3-glycan epitope of HIV-1 Env protein. This antibody has been determined by Enzyme-linked immunosorbent assay, Bio-layer interferometry and Neutralization assay. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | HIV-1 |
| Epitope | V3-glycan |
| Isotype | Human IgG |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA; BLI; Neut |
| Application Notes | Bio-layer interferometry (BLI): The bio-sensors were immersed in PBS pH 7.4 containing IgGs at 10 μg/mL for 1 minutes and 1000 rpm prior to encounter the analyte. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | HIV-1 Env |
| Alternative Name | Human immunodeficiencyvirus-1 envelope protein |
| Research Area | Infectious Disease |
| Related Disease | Acquired Immune Deficiency Syndrome |
