| Description | This product is a human antibody that binds to HIV-1 Env V3. The V3 region of the HIV-1 envelope is highly conserved as it is the coreceptor binding site and is highly immunogenic. 1F2C is most effective against the 25710.2.43 and 6535.3 viruses. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human immunodeficiency virus type 1 (HIV1) |
| Cross Reactivity | HIV-1 Subtype B (6535.3), HIV-1 Subtype C (25710.2.43) |
| Epitope | V3 domain |
| Isotype | Human IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | ELISA; Neut |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | HIV-1 Env |
| Alternative Name | HIV-1 envelope variable region 3; HIV-1; envelope; variable region 3; V3; hiv |
| Research Area | Microbiology |
