Description | N49P6 defines a new class of near-pan-neutralizing, plasma-deconvoluting CD4bs antibodies, which we refer to as the N49P series. N49P6 exhibits remarkable breadth in part by mimicking the quaternary interaction of CD4 with neighboring gp120 protomers. |
Clonality | Monoclonal |
Host Species | Human |
Target Species | Human Immunodeficiency Virus (HIV) |
Isotype | IgG |
Expression Species | HEK293F or CHO cell line |
Conjugation | Unconjugated |
Purity | >95% |
Endotoxin | <1 EU/mg |
Form | Liquid |
Purification | Protein A purified |
Sterility | 0.2 μM filtered |
Formulation | PBS, pH 7.4 |
Preservation | No preservatives |
Stabilizer | No stabilizers |
Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
Application | ELISA; WB; Neut |
ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
WB | Western Blot Protocol |
FC | Flow Cytometry Protocol |
Target | HIV CD4bs |
Alternative Name | Human immunodeficiency virus; HIV |
Research Area | Microbiology |