Description | This is a Monkey antibody that specifically targets HIV/SIV Env. It has the ability to neutralize the SIVmac239 strain. Among the two conserved PNGS sequons found in both HIV-1 and SIV gp120 cores, the antibody specifically recognizes the one located at glycan N88. The other sequon at N262 is situated at the center of the heavily glycosylated "silent face". |
Clonality | Monoclonal |
Host Species | Monkey |
Target Species | Human immunodeficiency virus (HIV), Simian immunodeficiency virus (SIV) |
Epitope | glycan N88 |
Isotype | Monkey IgG |
Expression Species | HEK293F or CHO |
Conjugation | None |
Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
Endotoxin | <1 EU/mg |
Purification | Protein A or G purified |
Sterility | 0.2 μM filtered |
Formulation | PBS, pH 7.4 |
Preservation | No preservatives |
Stabilizer | No stabilizers |
Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
Application | ELISA; Neut |
ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
WB | Western Blot Protocol |
FC | Flow Cytometry Protocol |
Target | HIV/SIV Env |
Alternative Name | ENV; gp160; envelope glycoprotein; Envelope surface glycoprotein gp160; precursor; hypothetical protein; Envelope surface glycoprotein gp120; Envelope transmembrane domain; HIV-1; HIV; AIDs; Human immunodeficiency virus 1; SIVmac239 gp140; SIVmac239; gp140; SIV; Envelope |
Research Area | Microbiology |