| Description | This is a Monkey antibody that specifically targets HIV/SIV Env. It has the ability to neutralize the SIVmac239 strain. Among the two conserved PNGS sequons found in both HIV-1 and SIV gp120 cores, the antibody specifically recognizes the one located at glycan N88. The other sequon at N262 is situated at the center of the heavily glycosylated "silent face". |
| Clonality | Monoclonal |
| Host Species | Monkey |
| Target Species | Human immunodeficiency virus (HIV), Simian immunodeficiency virus (SIV) |
| Epitope | glycan N88 |
| Isotype | Monkey IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A or G purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | ELISA; Neut |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | HIV/SIV Env |
| Alternative Name | ENV; gp160; envelope glycoprotein; Envelope surface glycoprotein gp160; precursor; hypothetical protein; Envelope surface glycoprotein gp120; Envelope transmembrane domain; HIV-1; HIV; AIDs; Human immunodeficiency virus 1; SIVmac239 gp140; SIVmac239; gp140; SIV; Envelope |
| Research Area | Microbiology |