| Description | This product is a human neutralizing antibody which binds HIV-1 Envelope. Its binding epitope is quaternary epitope at Env trimer apex. It shows high affinity with HIV-1 Env protein and neutralizing potency against HIV-1. This product has been determined using Surface plasmon resonance and Neutralization assay. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | HIV1 |
| Epitope | Quaternary epitope at Env trimer apex |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA; SPR; Neut |
| Application Notes | The antibody was tested by SPR and Neutralization assay. Pseudoviruses were harvested 48-72 hr post-transfection, filtered, and titrated for use in neutralization assays. Neutralization was measured in TZM-bl target cells. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | HIV1 Env |
| Alternative Name | Human immunodeficiencyvirus-1 envelope |
| Research Area | Infectious Disease |
| Related Disease | Acquired Immune Deficiency Syndrome |
