| Description | This antibody is a neutralizing IgG specific for HIV-1 Envelope, derived from human. The mAb specifically interacts with residues of the 324GDIR327 motif at the base of V3, part of the co-receptor binding site. It has potent neutralizing efficiency against HIV-1. This product has been tested using Enzyme-linked immunosorbent assay, Bio-layer interferometry and Neutralization assay. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | HIV1 |
| Epitope | GDIR motif (a.a. 324-327) |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA; BLI; Neut |
| Application Notes | The Bio-layer interferometry (BLI) was done using the mAb at a concentration of 10 μg/mL. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | HIV1 Env |
| Alternative Name | Human immunodeficiencyvirus-1 envelope |
| Research Area | Infectious Disease |
| Related Disease | Acquired Immune Deficiency Syndrome |
