Recombinant Anti-HLA-DR-β Antibody (V3S-1022-YC1441) (CAT#: V3S-1022-YC1441)

Send Inquiry
  • fig1






Description This antibody is a humanized version of 1D10 was produced using CDR grafting from murine 1D10. The resulting antibody has an affinity that is similar to that of the parental murine antibody. hu1D10 recognizes some, but not all, of the human HLA-DR β chains. Both normal and malignant B cells can express the 1D10 antigen. In addition, the humanized antibody is capable of inducing complement-mediated cytotoxicity, antibody-dependent cell cytotoxicity, and direct apoptosis of 1D10-expressing B cells.
This product is a recombinant human antibody provided by CreativeBiolabs. It was expressed in mammalian cells (293F or CHO) with antibody encoding genes and purified by affinity chromatography. Each lot of this antibody is quality control tested by SDS-PAGE and SEC-HPLC analysis. For highly sensitive assays, we recommend the ultrapurified form of the product, which has a lower endotoxin limit than standard antibody, less than 1 EU/mg or even 0.1 EU/mg.
Clonality Monoclonal
Host Species Human
Target Species Human
Isotype IgG


Expression Species HEK293F or CHO Cell line
Conjugation Unconjugated, also available for Biotin, HRP, FITC and PE-labeled form.
Purity >95%, determined by SDS-PAGE and SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Purified with Protein A or G affinity chromatography
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.


Application FC; ELISA


ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol


Target HLA-DR-β
Alternative Name HLA-DR β chain; HLA-DR beta chain
Research Area Cardiovascular; Signal Pathway
For research use only, not directly for clinical use.
banner banner
© 2024 Creative Biolabs. All Rights Reserved.
Online Inquiry