| Description | This product is a IAV H5N1 HA broadly neutralizing antibody. The monoclonal antibody bound to the head group have binding and neutralizing activities at 2.30-Å resolution. The antibody can inhibit viral attachment and the post-attachment fusion step. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Influenzavirus A Subtype H5N1 |
| Epitope | AA 55-271 (A/Anhui/1/2005 HA) |
| Neutralization Mechanism | AVFluIgG01 inhibits HA-mediated membrane fusion in a dose-dependent manner and prevents the acquisition of pH-induced protease sensitivity. |
| IC50 | 0.012 ± 0.016 ug/mL |
| Isotype | Human IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | Neut |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | IAV H5N1 HA |
| Alternative Name | Influenza A virus Hemagglutinin; Influenza A virus; Hemagglutinin; HA; IAV; H5; H5N1; IAV H5N1 |
| Research Area | Microbiology |
