Anti-KIR3DL2 Neutralizing Antibody (V3S-0522-YC1725) (CAT#: V3S-0522-YC1725)

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Datasheet

MSDS

COA

Sub Cat Immunogen Epitope Isotype Application  
V3S-1124-YC809 Recombinant human KIR3DL2 extracellular domain recombinant protein The epitope includes residues 1150 and/or M128. IgG2a kappa FC; Inhib; FuncS Inquiry
V3S-0622-YC319 IgG2b ELISA; FC; FuncS Inquiry
V3S-0522-YC1727 Recombinant human KIR3DL2 extracellular domain recombinant protein In the DO domain including residues F9, S11, Q56 and/or E57, in addition to A25, Q27, 160 and/or G62. IgG FC Inquiry
V3S-0522-YC1726 Recombinant human KIR3DL2 extracellular domain recombinant protein In the ECD domain. IgG1 kappa FC Inquiry
V3S-0522-YC1728 Recombinant human KIR3DL2 extracellular domain recombinant protein The epitope includes residues V147 and/or Q149. IgG FC Inquiry
V3S-0522-YC6455 Polyclonal IL-2 activated NK population IgG FC Inquiry
V3S-0622-YC318 IgG1 ELISA; FC; IHC Inquiry
V3S-1022-YC357 IgG1 FC; ELISA Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description This product is a monoclonal antibody derived from Mouse (Mus musculus), which can specifically recognize Killer Cell Immunoglobulin Like Receptor, Three Ig Domains And Long Cytoplasmic Tail 2. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation.
Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free.
Clonality Monoclonal
Host Species Mouse
Target Species Human
Immunogen Recombinant human KIR3DL2 extracellular domain recombinant protein
Epitope The epitope of antibody can include residues 1150 and/or M128.
Isotype IgG2a, κ

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.

Applications

Application FC; Inhib; FuncS
Application Notes The antibody is recommended for detection of KIR3DL2 by FC, Inhib, FuncS assays.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target KIR3DL2
Alternative Name Killer Cell Immunoglobulin Like Receptor, Three Ig Domains And Long Cytoplasmic Tail 2; Killer Cell Immunoglobulin-Like Receptor, Three Domains, Long Cytoplasmic Tail, 2; P70 Natural Killer Cell Receptor Clone CL-5; Natural Killer-Associated Transcript 4; CD158 Antigen-Like Family Member K; MHC Class I NK Cell Receptor; P70 NK Receptor CL-5; CD158K; NKAT-4; NKAT4; Killer Cell Immunoglobulin-Like Receptor 3DL2
Gene ID 3812
UniProt P43630
Research Area Immunology
Related Disease Cancer, Inflammatory disease
For research use only, not directly for clinical use.
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