| Description | This product is a human antibody that specifically targets LASV GP. The antibody, known as 37.7H, exhibits reduced effectiveness in neutralization assays compared to antibody 18.5C, which is derived from survivor LS011 and is the least potent among the three. It binds to LASV GPCysR4 with an affinity of 9.8 nM. 25.6A exhibited slightly weaker binding, with a KD-Wavg of approximately 10 nM. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Lassa mammarenavirus (LASV) |
| Affinity | KD= 9.8 nM (LASV GPCysR4) |
| Isotype | Human IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | ELISA; Neut (weakly) |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | LASV GP |
| Alternative Name | Lassa virus glycoprotein; Lassa virus; glycoprotein; LASV; GP |
| Research Area | Microbiology |
