Anti-LINGO1 Neutralizing Antibody (V3S-0522-YC1468) (CAT#: V3S-0522-YC1468)

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Datasheet

MSDS

COA

Sub Cat Isotype Application  
V3S-1124-YC1404 IgG1 kappa ELISA; IHC; FC; IP; IF; Block Inquiry
V3S-0522-YC7494 IgG1 WB; Block; FuncS Inquiry
V3S-0622-YC4898 IgG FuncS Inquiry
V3S-1222-YC102 IgG1 IHC; WB; IP; EM; Neut Inquiry
V3S-0522-YC7819 IgG1 ELISA Inquiry
V3S-0522-YC7820 IgG1 WB; ELISA; IF; FuncS Inquiry
V3S-1022-YC1076 IgG WB; ELISA Inquiry
V3S-1022-YC1333 IgG WB; ELISA; IF Inquiry
V3S-1022-YC1334 IgG WB; ELISA; IF Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description This product is a monoclonal antibody derived from Human (Homo sapiens), which can specifically recognize leucine rich repeat and Ig domain containing 1. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation.
Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free.
Clonality Monoclonal
Host Species Human
Target Species Human
Isotype IgG1, κ

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.

Applications

Application ELISA; IHC; FC; IP; IF; Block
Application Notes The antibody is recommended for detection of LINGO1 by ELISA, IHC, FC, IP, IF, Block assays.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target LINGO1
Alternative Name LINGO1; leucine rich repeat and Ig domain containing 1; LERN1; LRRN6A; UNQ201; leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; leucine rich repeat neuronal 6A; leucine-rich repeat neuronal protein 1; leucine-rich repeat and immunoglobulin domain-containing protein 1; Li81; Li33
Gene ID 84894
UniProt Q96FE5
Research Area Neuroscience
Related Disease Relapsing-Remitting Multiple Sclerosis, Acute Optic Neuritis
For research use only, not directly for clinical use.
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