Anti-NOTCH4 Neutralizing Antibody (V3S-1022-YC2341) (CAT#: V3S-1022-YC2341)

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Datasheet

MSDS

COA

Sub Cat Target Species Isotype Application Affinity  
V3S-1124-YC659 Human, Mouse, Cynomolgus IgG2 Neut; IF 0.44 nM Inquiry
V3S-0522-YC1883 Human, Mouse IgG ELISA; FuncS Inquiry
V3S-1022-YC2340 Human IgG2 kappa Neut Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description This product is a recombinant Human antibody provided by CreativeBiolabs. The antibody is specific for Notch 4. It can be used for Notch 4 detection in Neutralization Assay and Immunofluorescence. It was expressed in mammalian cells (293F or CHO) with antibody encoding genes and purified by affinity chromatography. Each lot of this antibody is quality control tested by SDS-PAGE and SEC-HPLC analysis. For highly sensitive assays, we recommend the ultrapurified form of the product, which has a lower endotoxin limit than standard antibody, less than 1 EU/mg or even 0.1 EU/mg.
Clonality Monoclonal
Host Species Human
Target Species Human, Mouse, Cynomolgus
Affinity The affinity is in nanomolar range, about 0.44 nM, determined by surface plasmon resonance.
Isotype IgG2

Property

Expression Species HEK293F or CHO Cell line
Conjugation Unconjugated, also available for Biotin, HRP, FITC and PE-labeled form.
Purity >95%, determined by SDS-PAGE and SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Purified with Protein A or G affinity chromatography
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.

Applications

Application Neut; IF

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target NOTCH4
Alternative Name INT3
Gene ID 4855
UniProt Q99466
Research Area Cell Biology
Related Disease Cancer
For research use only, not directly for clinical use.
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