Anti-NTRK1 (NGF docking site) Neutralizing Antibody (V3S-0622-YC405) (CAT#: V3S-0622-YC405)

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Description This product is a human monoclonal antibody that reacts with NTRK1. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation.
Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free.
Clonality Monoclonal
Host Species Human
Target Species Human
Immunogen Human TrkA expressing tumor cells.
Epitope Located in NGF docking site.
Isotype IgG1 kappa


Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.


Application Agonist; IHC; IF; Inhib
Application Notes The antibody is recommended for detection of NTRK1 by Agonist, IHC (1/20-1/200), IF (1/100-1/500), Inhib assays.


ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol


Target NTRK1
Alternative Name MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA; high affinity nerve growth factor receptor; Oncogene TRK; TRK1-transforming tyrosine kinase protein; gp140trk; neurotrophic tyrosine kinase, receptor, type 1; tropomyosin-related kinase A; tyrosine kinase receptor A
Gene ID 4914
UniProt P04629
Related pathway MAPK pathway
Research Area Neuroscience; Cancer Research
For research use only, not directly for clinical use.
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