| Sub Cat | Immunogen | Isotype | Application | Affinity | |
|---|---|---|---|---|---|
| V3S-1124-YC412 | IgM | ELISA; IF | |||
| V3S-0522-YC777 | IgG | ELISA | |||
| V3S-0522-YC940 | IgG1 kappa | ELISA; FC | |||
| V3S-0522-YC960 | P. berghei chimeric sporozoites expressing P. falciparum CSP (3D7 strain) | IgG1 kappa | ELISA; FuncS | ||
| V3S-0522-YC961 | IgG1 kappa | ELISA; IF | |||
| V3S-0522-YC979 | IgG1 lambda | ELISA; FC | 0.23 nM | ||
| V3S-0522-YC980 | P. berghei chimeric sporozoites expressing P. falciparum CSP (3D7 strain) | IgG1 lambda | ELISA; FuncS |
| Description | This product is a monoclonal antibody derived from Human (Homo sapiens), which can specifically recognize P. falciparum circumsporozoite protein. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation. Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Plasmodium falciparum |
| Isotype | IgM |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and/or SEC-HPLC |
| Endotoxin | <1 EU/mg, determined by LAL method |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C. |
| Application | ELISA; IF |
| Application Notes | The antibody is recommended for detection of PfCSP by ELISA, IF assays. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | PfCSP |
| Alternative Name | P. falciparum circumsporozoite protein; PfCSP |
| UniProt | P02893 |
| Research Area | Infectious Disease |
| Related Disease | Malaria |
