| Description | The product is an vaccine-induced human mAb to PfRH5. The antibody binds to PfRH5 at the tip of the "kite-like" structure, interacting with the N terminus of helix 4 and the three loops that connect the converging helices at this apex of PfRH5. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Plasmodium falciparum |
| Epitope | R5.004 binds to a distinct epitope, contacting the N terminus of helix 4 and each of the three loops that link the converging helices at this apex of PfRH5. |
| EC50 | 22.3 μg/mL |
| Affinity | KD = 0.636 nM |
| Isotype | Human IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | ELISA; DB; Neut |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | PfRH5 |
| Alternative Name | Plasmodium falciparum reticulocyte-binding protein homolog 5; RH5; reticulocyte-binding protein homolog 5 |
| Research Area | Immunology |
