| Description |
This product is a monoclonal antibody derived from Human (Homo sapiens), which can specifically recognize phosphorylated Microtubule Associated Protein Tau. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation.
Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free. |
| Epitope |
The epitope was mapped to a region comprising amino acid residues 404-411 of the longest isoform of human Tau (TAU441), with S409 phosphorylated (pS409), and preferential binding to Tau amino acid residues, H407, pS409, N410, and V411. |
