Description | The antibody m396-B10 is a human mAb specific for SARS-CoV-2 Spike S1 protein. It displayed high monovalent binding affinity to soluble SARS-CoV-2 RBD with KDs in the low nanomolar range. It also potently neutralized both SARS-CoV-1 and SARS-CoV-2 pseudoparticles. |
Clonality | Monoclonal |
Host Species | Human |
Target Species | SARS-CoV-2 |
Cross Reactivity | SARS-CoV-1 |
Epitope | Receptor-binding domain (RBD) |
Function | Potently neutralized both SARS-CoV-1 and SARS-CoV-2 pseudoparticles. |
Isotype | IgG1 |
Expression Species | HEK293F or CHO cell line |
Conjugation | Unconjugated |
Purity | >95% |
Endotoxin | <1 EU/mg |
Form | Liquid |
Purification | Protein A purified |
Sterility | 0.2 μM filtered |
Formulation | PBS, pH 7.4 |
Preservation | No preservatives |
Stabilizer | No stabilizers |
Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
Application | ELISA, Neut |
ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
WB | Western Blot Protocol |
FC | Western Blot Protocol |
Target | SARS-CoV-2 |
Alternative Name | Severe acute respiratory syndrome coronavirus 2 |
Research Area | Coronavirus Disease 2019 |
Related Disease | Coronavirus Disease 2019 |