Anti-SARS-CoV-2 Spike S1 (RBD) Neutralizing Antibody (V3S-0623-XY53) (CAT#: V3S-0623-XY53)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target

Summary

Description The antibody MB.02 is a human mAb specific for SARS-CoV-2 Spike S1 protein. It maintains high activity against BA.2. It mainly contacts a flexible loop region at the left shoulder region of spike RBD. The antibody-binding interface on spike RBD has no overlap with the ACE2-binding interface.
Clonality Monoclonal
Host Species Human
Target Species Omicron BA.2
Epitope The antibody binds to spike RBD but does not overlap with the ACE2-binding interface.
Isotype IgG1

Property

Expression Species HEK293F or CHO cell line
Conjugation Unconjugated
Purity >95%
Endotoxin <1 EU/mg
Form Liquid
Purification Protein A purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.

Applications

Application ELISA, Neut
Application Notes The EC50 of MB.02 against BA.2 is 3 ng/mL.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Western Blot Protocol

Target

Target SARS-CoV-2
Alternative Name Severe acute respiratory syndrome coronavirus 2
Research Area Coronavirus Disease 2019
Related Disease Coronavirus Disease 2019
For research use only, not directly for clinical use.
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