| Description | The antibody ADG20 is a human mAb specific for SARS-CoV-2 Spike S1 protein. It targets one corner of the RBD that is distant from the ridge region through CDRs H1, H2, H3, L1, and L3. It exhibits high potency to CoVs that include SARS-CoV-2, Alpha, Beta, Gamma, and Delta VOCs, and other SARS related coronaviruses including SARS-CoV-1, pang17, and WIV1. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | SARS-CoV-2 |
| Cross Reactivity | Alpha, Beta, Gamma, and Delta VOCs, SARS-CoV-1, pang17 and WIV1. |
| Epitope | Receptor-binding domain (RBD) |
| Isotype | IgG1 |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA, Neut |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Western Blot Protocol |
| Target | SARS-CoV-2 |
| Alternative Name | Severe acute respiratory syndrome coronavirus 2 |
| Research Area | Coronavirus Disease 2019 |
| Related Disease | Coronavirus Disease 2019 |
