Anti-SARS-CoV-2 Spike S1 (RBD) Neutralizing Antibody (V3S-0623-XY113) (CAT#: V3S-0623-XY113)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target

Summary

Description The antibody CV07-270 is a human mAb specific for SARS-CoV-2 Spike S1 protein. The binding of mAbs to unfixed murine tissues was tested. The result revealed it is reactive to smooth muscle from sections of lung, heart, kidney, and colon but not liver. It uses CDR H1, H3, L1, and L2 for RBD interaction. It (IC50 = 82.3 ng/mL) had only 2 SHMs (2/0), did not reduce ACE2 binding in our assay, and showed binding to smooth muscle tissue.
Clonality Monoclonal
Host Species Human
Target Species SARS-CoV-2
Epitope Receptor-binding domain (RBD)
Isotype IgG1

Property

Expression Species HEK293F or CHO cell line
Conjugation Unconjugated
Purity >95%
Endotoxin <1 EU/mg
Form Liquid
Purification Protein A purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.

Applications

Application ELISA, Neut
Application Notes The IC50 value of CV07-270 is 82.3 ng/mL.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Western Blot Protocol

Target

Target SARS-CoV-2
Alternative Name Severe acute respiratory syndrome coronavirus 2
Research Area Coronavirus Disease 2019
Related Disease Coronavirus Disease 2019
For research use only, not directly for clinical use.
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