| Description | The antibody P2G3 is a human mAb specific for SARS-CoV-2 Spike S1 protein. It is a potent monoclonal neutralizing antibody. The antibody displayed the most potent activity in assays performed with the spike protein from Omicron BA.1, BA.1.1 that includes the R346K mutation and BA.2. It had potent neutralizing activity against lentiviruses pseudotyped with spike from the initial 2019-nCoV (D614G), Alpha, Beta and Delta VOCs (IC80 value of 0.022, 0.051, 0.038 and 0.035 µg/ml, respectively). |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Omicron BA.1, BA.1.1 |
| Cross Reactivity | 2019-nCoV (D614G), Alpha, Beta and Delta VOCs |
| Epitope | Receptor-binding domain (RBD) |
| Isotype | IgG1 |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA, Neut |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Western Blot Protocol |
| Target | SARS-CoV-2 |
| Alternative Name | Severe acute respiratory syndrome coronavirus 2 |
| Research Area | Coronavirus Disease 2019 |
| Related Disease | Coronavirus Disease 2019 |
