| Description | This product is a recombinant rabbit antibody provided by CreativeBiolabs. The antibody is specific for Sodium Voltage-Gated Channel Alpha Subunit 9, this gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. It can be used for SCN9A detection in Enzyme-Linked Immunosorbent Assay. It was expressed in mammalian cells (293F or CHO) with antibody encoding genes and purified by affinity chromatography. Each lot of this antibody is quality control tested by SDS-PAGE and SEC-HPLC analysis. For highly sensitive assays, we recommend the ultrapurified form of the product, which has a lower endotoxin limit than standard antibody, less than 1 EU/mg or even 0.1 EU/mg. |
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Target Species | Human |
| Immunogen | E1 extracellular loop of human sodium ion channel Nav 1.7 |
| Isotype | IgG1 |
| Expression Species | HEK293F or CHO Cell line |
| Conjugation | Unconjugated, also available for Biotin, HRP, FITC and PE-labeled form. |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg, determined by LAL method |
| Purification | Purified with Protein A or G affinity chromatography |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | SCN9A |
| Alternative Name | Sodium Voltage-Gated Channel Alpha Subunit 9; Sodium Channel, Voltage-Gated, Type IX, Alpha Polypeptide; Sodium Channel, Voltage-Gated, Type IX, Alpha Subunit; Voltage-Gated Sodium Channel Subunit Alpha Nav1.7; Sodium Channel Protein Type IX Subunit Alpha; Neuroendocrine Sodium Channel; Peripheral Sodium Channel 1; HNE-Na; NENA; PN1; Sodium Channel, Voltage Gated, Type IX Alpha Subunit |
| Gene ID | 6335 |
| UniProt | Q15858 |
| Research Area | Cell Biology; Immunology |
| Related Disease | Neuropathic pain |
