In the peptide corresponds to amino acid residues 175-181 and has the amino acid sequence of: GPENSGK.
IgG
ELISA; FC; Block
2.92 nM
Inquiry
V3S-0522-YC1895
In the peptides correspond to amino acid residues 207-227 and 237-260 and has the amino acid sequences of: FVQTDLPFHPLTQMMYSPQNS and NGLWVSKNFGGKWEEIHKAVCLAK.
IgG
ELISA; FC; Block
Inquiry
V3S-0522-YC1903
In the peptide corresponds to amino acid residues 212-221 and has the amino acid sequence of: LPFHPLTQMM.
IgG
ELISA; FC; Block
3.51 nM
Inquiry
V3S-0522-YC1901
In the peptide corresponds to amino acid residues 233-243 and has the amino acid sequence of: LSTENGLWVSK.
IgG
ELISA; FC; Block
1.34 nM
Inquiry
V3S-0522-YC1893
In the peptides correspond to amino acid residues 237-260 and 297-317 and has the amino acid sequences of: NGLWVSKNFGGKWEEIHKAVCLAK and KTIGVKIYSFGLGGRFLFASV. Further, the cross-linked residues within the peptides correspond to residues K243 and K248 within amino acid residues 237-260 and residues S305, R311, and S316 within amino acid residues 297-317.
IgG
ELISA; FC; Block; FuncS
11 pM
Inquiry
V3S-0522-YC1894
In the peptides correspond to amino acid residues 237-247 and 314-338 and has the amino acid sequences of: NGLWVSKNFGG and FASVMADKDTTRRIHVSTDQGDTWS. Further, the cross-linked residues within the peptides correspond to residues S242 and K243 within amino acid residues 237-247 and residues S316 and R325 within amino acid residues 314-338.
IgG1
ELISA; FC; Block
0.23 nM
Inquiry
V3S-0522-YC1897
In the peptide corresponds to amino acid residues 367-391 and has the amino acid sequence of: EPGDTGFGTIFTSDDRGIVYSKSLD. Further, the cross-linked residues within the peptide corresponds to residues S379, R382, and Y386 within amino acid residues 367-391.
IgG
ELISA; FC; Block
Inquiry
V3S-0522-YC1898
In the peptide corresponds to amino acid residues 623-632 and has the amino acid sequence of: HSTDPEDYED.
IgG
ELISA; FC; Block
18.1 nM
Inquiry
V3S-0522-YC1900
In the peptide corresponds to amino acid residues 740-749 and has the amino acid sequence of: CTSNFLSPEK.
IgG
ELISA; FC; Block
7.81 nM
Inquiry
Summary
Property
Applications
Protocols
Target
Summary
Description
This product is a monoclonal antibody derived from Human (Homo sapiens), which can specifically recognize Sortilin 1. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation. Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free.
Clonality
Monoclonal
Host Species
Human
Target Species
Human, Mouse
Epitope
The epitope is in the peptide corresponds to amino acid residues 175-181 and has the amino acid sequence of: GPENSGK.
Affinity
KD = 2.92 nM, determined by surface plasmon resonance.
Isotype
IgG
Property
Expression Species
HEK293F or CHO
Conjugation
None
Purity
>95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin
<1 EU/mg, determined by LAL method
Purification
Protein A affinity purified
Sterility
0.2 μM filtered
Formulation
PBS, pH 7.4
Preservation
No preservatives
Stabilizer
No stabilizers
Storage
Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.
Applications
Application
ELISA; FC; Block
Application Notes
The antibody is recommended for detection of SORT1 by ELISA, FC, Block assays.
