| Sub Cat | Target Species | Immunogen | Isotype | Application | |
|---|---|---|---|---|---|
| V3S-1124-YC216 | Human, Cynomolgus, Mouse | Recombinant human RANKL | IgG | ELISA; Neut; Inhib | |
| V3S-0622-YC544 | Human, Cynomolgus, Mouse | IgG2 kappa | ELISA; FC; Neut; FuncS | ||
| V3S-0522-YC1973 | Human, Cynomolgus | CHO cells expressing the full-length human OPGL | IgG2 kappa | ELISA; Neut | |
| V3S-0622-YC546 | Human, Cynomolgus | IgG1 kappa | ELISA; FC; Neut; FuncS |
| Description | This product is a monoclonal antibody derived from Human (Homo sapiens), which can specifically recognize Tumor necrosis factor superfamily member 11. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation. Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human, Cynomolgus, Mouse |
| Immunogen | Recombinant human RANKL |
| Isotype | IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and/or SEC-HPLC |
| Endotoxin | <1 EU/mg, determined by LAL method |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C. |
| Application | ELISA; Neut; Inhib |
| Application Notes | The antibody is recommended for detection of TNFSF11 by ELISA, Neut, Inhib assays. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | TNFSF11 |
| Alternative Name | TNF Superfamily Member 11; Tumor Necrosis Factor (Ligand) Superfamily, Member 11; TNF-Related Activation-Induced Cytokine; Osteoclast Differentiation Factor; Osteoprotegerin Ligand; TRANCE; RANKL; OPGL; ODF; Receptor Activator Of Nuclear Factor Kappa B Ligand; Receptor Activator Of Nuclear Factor Kappa-B Ligand |
| Gene ID | 8600 |
| UniProt | O14788 |
| Research Area | Immunology; Cardiovascular |
| Related Disease | Bone Loss Disease |
