| Description | This product is a human monoclonal antibody that recognizes Acinetobacter baumannii. It can inhibit the activity of Acinetobacter baumannii in vitro. The antibody showed moderate binding and growth inhibitory activity against K. pneumoniae and P. aeruginosa.The combination of CS with this antibody led to a synergistic effect against Acinetobacter baumannii A.b.56. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | A. baumannii |
| Immunogen | Acinetobacter baumannii |
| Epitope | A. baumannii A.b.56 |
| Affinity | FICI value of the combination of colistin sulfate is 0.5. |
| Isotype | Human IgG |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservative |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | DB; WB; Inhib |
| Application Notes | This antibody had high inhibition activity against Acinetobacter baumannii A.b.56 at 200 µg/ml. It also showed approximately 15% reduction at 100 µg/ml, while no activity against Acinetobacter baumannii A.b.56 was observed at 25 µg/ml. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | A. baumannii |
| Alternative Name | Acinetobacter baumannii |
| Research Area | Microbiology |
| Related Disease | CRAB pneumonia and bloodstream infection |
