| Description | The product is a human antibody against Alzheimer's Aβ fibrils with strict conformational and sequence specificity. It exhibited a higher apparent affinity in comparison to the maternal antibody. The affinity matured antibody displayed a high level of conformational specificity, similar to clone 97. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human |
| Epitope | The antibody displayed high conformational specificity. |
| EC50 | 18 ± 1 nM to Aβ fibrils |
| Isotype | Human IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | ELISA; DB; WB; IF |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | Abeta fibril |
| Alternative Name | Aβ fibril; Aβ fibrils; β-amyloid (Aβ) fibrils; β-amyloid fibrils; Aβ; amyloid beta |
| Research Area | Neuroscience |
