Description | The product is a human antibody against Alzheimer's Aβ fibrils with strict conformational and sequence specificity. It exhibited a higher apparent affinity in comparison to the maternal antibody. The affinity matured antibody displayed a high level of conformational specificity, similar to clone 97. |
Clonality | Monoclonal |
Host Species | Human |
Target Species | Human |
Epitope | The antibody displayed high conformational specificity. |
EC50 | 18 ± 1 nM to Aβ fibrils |
Isotype | Human IgG |
Expression Species | HEK293F or CHO |
Conjugation | None |
Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
Endotoxin | <1 EU/mg |
Purification | Protein A purified |
Sterility | 0.2 μM filtered |
Formulation | PBS, pH 7.4 |
Preservation | No preservatives |
Stabilizer | No stabilizers |
Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
Application | ELISA; DB; WB; IF |
ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
WB | Western Blot Protocol |
FC | Flow Cytometry Protocol |
Target | Abeta fibril |
Alternative Name | Aβ fibril; Aβ fibrils; β-amyloid (Aβ) fibrils; β-amyloid fibrils; Aβ; amyloid beta |
Research Area | Neuroscience |