| Description | This is a human monoclonal antibody that targets to human ACHR. It can block the binding of 33% of the MG autoantibodies. The antibody protects the hAChR against the antigenic modulatory activity of MG autoantibodies. The clone has a epitope that is located within a highly immunogenic region on the hAChR, which does not coincide with the MIR. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human |
| Isotype | Human IgG, lambda |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | RIA; ELISA |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | AChR |
| Alternative Name | acetylcholine receptor; ACh receptor |
