| Description | This is a human IgG1 monoclonal antibody that targets the human ADDL protein. Gamma-adducin is encoded by the ADD3 gene in humans. Adducins are composed of different subunits known as adducin alpha, beta, and gamma, and are heteromeric proteins. These three subunits are encoded by separate genes. They are part of a family of membrane skeletal proteins that play a role in assembling the spectrin-actin network in erythrocytes and at cell-cell contact sites in epithelial tissues. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human |
| Isotype | Human IgG1 |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | FuncS |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | ADD3 |
| Alternative Name | Adducin 3; Adducin-Like Protein 70; Adducin 3 (Gamma); Gamma-Adducin; ADDL; CPSQ3 |
| Gene ID | 120 |
| UniProt | Q9UEY8 |
| Related pathway | Activation of cAMP-Dependent PKA and Signaling by Rho GTPases |
| Research Area | Cancer Research |
| Related Disease | Cerebral Palsy, Spastic Quadriplegic, 3 and Spastic Quadriplegic Cerebral Palsy |
