ADD3 Specific Recomb™ Antibody (V3S-0324-FY2), Human IgG1 (CAT#: V3S-0324-FY2)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target

Summary

Description This is a human IgG1 monoclonal antibody that targets the human ADDL protein. Gamma-adducin is encoded by the ADD3 gene in humans. Adducins are composed of different subunits known as adducin alpha, beta, and gamma, and are heteromeric proteins. These three subunits are encoded by separate genes. They are part of a family of membrane skeletal proteins that play a role in assembling the spectrin-actin network in erythrocytes and at cell-cell contact sites in epithelial tissues.
Clonality Monoclonal
Host Species Human
Target Species Human
Isotype Human IgG1

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and SEC-HPLC
Endotoxin <1 EU/mg
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within a week. For longer storage, aliquot and store at -20°C.

Applications

Application FuncS

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target ADD3
Alternative Name Adducin 3; Adducin-Like Protein 70; Adducin 3 (Gamma); Gamma-Adducin; ADDL; CPSQ3
Gene ID 120
UniProt Q9UEY8
Related pathway Activation of cAMP-Dependent PKA and Signaling by Rho GTPases
Research Area Cancer Research
Related Disease Cerebral Palsy, Spastic Quadriplegic, 3 and Spastic Quadriplegic Cerebral Palsy
For research use only, not directly for clinical use.
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