| Description | This human monoclonal antibody exhibits a binding affinity to CMV. The IgG forms of the antibody display apparent KD values of 5 nM. It has the capability to inhibit CTL-mediated cytotoxicity targeted at the HLA-A2-pp65 complex. The antibody's specificity towards the MHC-pp65 495-503 complex expressed on cells was additionally confirmed through the specific inhibition of CTL-mediated cell lysis by the antibody. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Cytomegalovirus (CMV) |
| Epitope | pp65 495-503, NLVPMVATV |
| Affinity | KD = 5 nM |
| Isotype | Human IgG1 |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | FC; ELISA |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | pp65 |
| Alternative Name | Cytomegalovirus; CMV |
| Research Area | Infectious disease |
| Related Disease | Cytomegalovirus disease |
