DLL3 (aa 391-427) Specific Recomb™ Antibody (V3S-0224-CJ6), Mouse IgG (CAT#: V3S-0224-CJ6)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target
Virus Background

Summary

Description Mouse anti-DLL3 antibody recognizes the EGF5 domain (aa 391-427) of human DLL3. The domain-level epitope mapping was determined by Flow Cytometry.
Clonality Monoclonal
Host Species Mouse
Target Species Human
Immunogen Human DLL3-fc protein (hDLL3-Fc)
Epitope EGF5 domain, aa 391-427 (conformational epitope)
Isotype Mouse IgG

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and SEC-HPLC
Endotoxin <1 EU/mg
Purification Protein G affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within a week. For longer storage, aliquot and store at -20°C.

Applications

Application ELISA; FC
Application Notes The antibody is recommended for detection of human DLL3 by ELISA.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target DLL3
Alternative Name SCDO1
Gene ID 10683
UniProt Q9NYJ7
Related pathway Gastrulation; Nervous system development
Research Area Neuroscience; Cell Biology
Related Disease Spondylocostal Dysostosis; Proliferative disorders

Virus Background

Post Translational Modification Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation.
For research use only, not directly for clinical use.
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