DLL3 (aa 216-249) Specific Recomb™ Antibody (V3S-0224-CJ8), Mouse IgG (CAT#: V3S-0224-CJ8)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target
Virus Background

Summary

Description This product is a mouse antibody that recognizes human DLL3 (delta like canonical Notch ligand 3). It maps to epitope found in the EGF1 domain (aa 216-249) as determined by Flow Cytometry.
Clonality Monoclonal
Host Species Mouse
Target Species Human
Immunogen Human DLL3-fc protein (hDLL3-Fc)
Epitope EGF1 domain, aa 216-249 (conformational epitope)
Isotype Mouse IgG

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and SEC-HPLC
Endotoxin <1 EU/mg
Purification Protein G affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within a week. For longer storage, aliquot and store at -20°C.

Applications

Application ELISA; FC
Application Notes The antibody has been used for ELISA, Flow Cytometry (DLL3 antibody: 50nM; Secondary antibody: 1 μg/mL).

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target DLL3
Alternative Name SCDO1
Gene ID 10683
UniProt Q9NYJ7
Related pathway Gastrulation; Nervous system development
Research Area Neuroscience; Cell Biology
Related Disease Spondylocostal Dysostosis; Proliferative disorders

Virus Background

Post Translational Modification Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation.
For research use only, not directly for clinical use.
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