DLL3 (aa 429-465) Specific Recomb™ Antibody (V3S-0224-CJ11), Mouse IgG (CAT#: V3S-0224-CJ11)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target
Virus Background

Summary

Description This mouse antibody was screened from hybridoma. This monoclonal antibody has been characterized to be specific to human DLL3. And the antibody binds to the EGF6 domain (aa 429-465) of hDLL3.
Clonality Monoclonal
Host Species Mouse
Target Species Human
Immunogen Human DLL3-fc protein (hDLL3-Fc)
Epitope EGF6 domain, aa 429-465 (conformational epitope)
Isotype Mouse IgG

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and SEC-HPLC
Endotoxin <1 EU/mg
Purification Protein G affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within a week. For longer storage, aliquot and store at -20°C.

Applications

Application ELISA; FC
Application Notes The epitope mapping of the antibody was measured by Flow Cytometry. The antibody also can be used in ELISA.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target DLL3
Alternative Name SCDO1
Gene ID 10683
UniProt Q9NYJ7
Related pathway Gastrulation; Nervous system development
Research Area Neuroscience; Cell Biology
Related Disease Spondylocostal Dysostosis; Proliferative disorders

Virus Background

Post Translational Modification Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation.
For research use only, not directly for clinical use.
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