Description | This product is a neutralizing antibody that binds to Human immunodeficiency virus-1 envelope glycoprotein. The antibody is a recombinant monkey mAb. The DH428 vaccine-induced lineage blocked CD4 binding and neutralized an autologous Tier-2 virus, but its genetic characteristics differed from those of most CD4bs nAbs. |
Clonality | Monoclonal |
Host Species | Monkey |
Target Species | HIV1 |
Epitope | Loop E and V5-loop |
Isotype | IgG |
Expression Species | HEK293F or CHO cell line |
Conjugation | Unconjugated |
Purity | >95% |
Endotoxin | <1 EU/mg |
Form | Liquid |
Purification | Protein A purified |
Sterility | 0.2 μM filtered |
Formulation | PBS, pH 7.4 |
Preservation | No preservatives |
Stabilizer | No stabilizers |
Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
Application | ELISA |
ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
WB | Western Blot Protocol |
FC | Flow Cytometry Protocol |
Target | HIV1 Env |
Alternative Name | HIV-1 envelope |
Research Area | Infectious Disease |
Related Disease | Acquired Immune Deficiency Syndrome |