| Description | This product is a neutralizing antibody that binds to Human immunodeficiency virus-1 envelope glycoprotein. ACS122 is capable of specifically binding with HIV-1 Env. The majority of the interactions are via ACS122 HC variable loops that interact with the gp41 fusion peptide proximal region (FPPR) and HR2 region. Most of the residues that ACS122 contacts in Env are highly conserved. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | HIV1 |
| Epitope | The gp41 fusion peptide proximal region (FPPR) and HR2 region |
| Isotype | IgG1 |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | HIV1 Env |
| Alternative Name | HIV-1 envelope |
| Research Area | Infectious Disease |
| Related Disease | Acquired Immune Deficiency Syndrome |
