| Description | SAM-6 is a mouse antibody that binds to deglycosylated Grp78. SAM-6 also detectably binds to apolipoprotein B100 (apoB100). Furthermore, SAM-6 detectably binds to LDL, VLDL, and deglycosylated LDL. SAM-6 binds to the cancer cell line A549. |
| Clonality | Monoclonal |
| Host Species | Mouse |
| Target Species | Human |
| Immunogen | The immunogen is respond to SAM-6/R glycoprotein. |
| Isotype | Mouse IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein G affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | FC; ELISA; IP; WB; IHC; Apop |
| Application Notes | ELISA: 12 μg/mL IHC: 50 μg/mL Apoptosis Assay: 100 μg/mL |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | HSPA5 |
| Alternative Name | Heat Shock Protein Family A (Hsp70) Member 5; Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa); Endoplasmic Reticulum Lumenal Ca(2+)-Binding Protein Grp78; Immunoglobulin Heavy Chain-Binding Protein; Glucose-Regulated Protein, 78kDa; GRP78; BIP; Heat Shock 70kD Protein 5 (Glucose-Regulated Protein, 78kD) |
| Gene ID | 3309 |
| UniProt | P11021 |
| Related pathway | Cancer Research |
| Research Area | Cancer Research |
| Related Disease | Diagnosis of neoplasia, tumour, cancer and disorders |
