adhesion G protein-coupled receptor E5

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Adgre5 is a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene.

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Anti-Adgre5 Neutralizing Antibody (V3S-0822-YC376) (CAT#: V3S-0822-YC376)

Target: Adgre5

Host Species: Mouse

Target Species: Mouse,

Application: Block,CyTOF,FC,