ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1

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ATP2A1 is one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.

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Anti-ATP2A1 Neutralizing Antibody (V3S-0822-YC394) (CAT#: V3S-0822-YC394)

Target: ATP2A1

Host Species: Mouse

Target Species: Human, Mouse, Dog, Rat, Guinea pig, Rabbit, Invertebrates,

Application: Block,ELISA,ICC,IF,IHC,IHC-Fr,IP,WB,

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Anti-ATP2A1 Neutralizing Antibody (V3S-0822-YC395) (CAT#: V3S-0822-YC395)

Target: ATP2A1

Host Species: Mouse

Target Species: Human, Mouse, Dog, Pig, Rat, Amphibians, Rabbit,

Application: Block,ELISA,ICC,IF,IHC,IHC-Fr,IHC-P,IP,WB,

For research use only, not directly for clinical use.