Complement Factor Bb

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Factor B is a component of the alternative pathway of complement. It contains a serine protease (SP) domain, and when activated it provides the catalytic activity of the alternative pathway C3 and C5 convertases. Factor B is generated as a single-chain protein, and cleavage by factor D generates two peptide fragments (Ba and Bb). The Bb region (which contains the SP domain) remains bound to C3(H2O) and C3b, forming the alternative pathway convertases [C3(H2O)Bb and C3bBb].

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Recombinant Anti-Bb Antibody (V3S-0522-YC2968) (CAT#: V3S-0522-YC2968)

Target: Bb

Host Species: Human

Target Species: Human, Cynomolgus, Rabbit,

Application: ELISA,FuncS,

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Recombinant Anti-Bb Antibody (V3S-0522-YC2969) (CAT#: V3S-0522-YC2969)

Target: Bb

Host Species: Human

Target Species: Human,

Application: FuncS,

For research use only, not directly for clinical use.